Immunity enhancement via hyposensitization: a promising approach for allergies and hay fever treatment
In a significant development for children suffering from grass and house dust mite allergies, sublingual immunotherapy (SLIT) has shown promising results in providing long-term benefits. This treatment, which involves administering allergen extracts under the tongue, has been found to offer sustained symptom relief and increased allergen tolerance that can last for years after treatment completion.
The treatment progresses through three phases: an initial adjustment phase (months 1-3) where early tolerance is built; a phase (3 months to 2 years) where symptoms substantially improve or resolve; and a long-term phase (3-5 years) where immune tolerance is established, leading to lasting symptom control.
Clinical evidence supports that SLIT reduces allergy symptoms, decreases medication use, and may alter the natural course of allergic disease in children. However, precise success rates vary by study and allergen, and insurance coverage for SLIT may impact accessibility.
SLIT is considered safe for children, with side effects generally mild and similar to those seen in adults. Common side effects include itching, swelling, redness, feeling tired, or weak on the treatment day. It's a preferred needle-free option, especially when antihistamines fail or injections are not tolerated.
It's essential to note that before starting SLIT, patients should inform their doctor about any medications they are taking, chronic illnesses, upcoming vacations or trips, sporting events, vaccinations, planned pregnancies, mouth discomfort, and any other relevant information.
Desensitization can be performed through Subcutaneous Immunotherapy (SCIT) or SLIT. However, SLIT is currently only approved for grass and house dust mite allergies and requires daily intake. SCIT, on the other hand, involves injecting the allergen under the skin.
While this treatment offers a significant improvement for many children, it should not be performed in cases of severe asthma, tumor diseases, cardiovascular weakness, kidney problems, a weakened immune system, or pregnancy.
In other news, a tractor overturned in Heidenheim, Baden-Württemberg, seriously injuring two children. Meanwhile, a meat truck tipped over on the A9 near Feucht, causing traffic disruptions. In sports, FC Teisbach and SV Etzenricht are both winless after the fourth matchday following a draw between the two teams.
References: [1] Long-term sublingual immunotherapy in children with grass and house dust mite allergies: a systematic review and meta-analysis. Allergy. 2018 Mar;73(3):484-496. doi: 10.1111/all.13409. Epub 2017 Nov 29. PMID: 29183819.
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Additional News:
- In SCIT, the allergen is injected under the skin, while in SLIT, it is administered under the tongue.
- Health insurance companies cover and pay for desensitization therapy, but the costs are determined by the individual case, treatment duration, and method chosen.
- Successful desensitization can be life-saving for allergies to bee or wasp venom.
- Desensitization therapy should not be performed in cases of severe asthma, tumor diseases, cardiovascular weakness, kidney problems, a weakened immune system, or pregnancy.
- The development of sublingual immunotherapy (SLIT) for children with grass and house dust mite allergies is significant in the field of workplace-wellness and medical-conditions.
- SLIT has shown long-term benefits for children, providing sustained relief from symptoms and increased allergen tolerance.
- The treatment progresses through three phases: initial adjustment (months 1-3), symptom improvement (3 months to 2 years), and lasting immune tolerance (3-5 years).
- Clinical evidence supports that SLIT reduces allergy symptoms, decreases medication use, and may alter the natural course of allergic diseases in children.
- Despite promising results, precise success rates vary by study and allergen, and insurance coverage may impact accessibility.
- SLIT is considered safe for children, with mild side effects that are similar to those seen in adults.
- Before starting SLIT, patients must inform their doctor about medications, chronic illnesses, vacations, sporting events, vaccinations, pregnancy plans, mouth discomfort, and other relevant information.
- Desensitization can be performed through Subcutaneous Immunotherapy (SCIT) or SLIT, but only the latter is approved for grass and house dust mite allergies and requires daily intake.
- SLIT offers a significant improvement for many children, but it should not be performed in cases of severe asthma, tumor diseases, cardiovascular weakness, kidney problems, a weakened immune system, or pregnancy.
- In Heidenheim, Baden-Württemberg, a tractor accident left two children seriously injured.
- On the A9 near Feucht, a meat truck overturned, causing traffic disruptions.
- In sports, FC Teisbach and SV Etzenricht drew after the fourth matchday.
- A councilor from Mannheim is organizing a FKK swingers trip to France, with 44-year-old Mimi from Rhineland-Palatinate joining.
- Over 600 firefighting athletes are competing for the German championship in Torgau, Saxony.
- The German-American Volksfest in Grafenwöhr is attracting visitors with music, culture, and culinary delights from America.
- Patients should wait for half an hour in the practice after injection therapy to prevent an allergic shock without supervision.
- In SCIT, the allergen is injected under the skin, while in SLIT, it is administered under the tongue.
- Health insurance companies cover and pay for desensitization therapy, but costs vary by case, treatment duration, and chosen method.
- Successful desensitization can be life-saving for allergies to bee or wasp venom.
- Desensitization therapy should not be performed in cases of severe asthma, tumor diseases, cardiovascular weakness, kidney problems, a weakened immune system, or pregnancy.
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